MSDS Cryopreserved Cells
Instructions HCF
Cell Apps Flyer Cardiovascular Cells
5 Important Cell Culture Rules
Cell Apps Poster Primary Cells
Cell Applications Inc Brochure
Description
Human Cardiac Fibroblasts (HCF) are the most prevalent cell type in the heart. HCF from Cell Applications, Inc. provide an excellent model system to study many aspects of human heart function and pathophysiology.
HCF from Cell Applications, Inc. have been utilized in a numerous published studies, for example to:
- Determine that electrical coupling between cardiomyocytes and fibroblasts is mediated by Ca2+-activated K+ channels that can be stimulated by estrogen receptor agonists
- Show that antimitogenic effects of estradiol on HCF growth are mediated by cytochromes and metabolites
- Demonstrate that in response to mechanical stretch, cardiac fibroblasts release TGF-β that downregulates trombomodulin, increases thromboembolism and induces cardiac fibroblast differentiation into myofibroblasts
- Indicate that activation of G protein-coupled receptor kinase-2 prevents normal regulation of collagen synthesis in cardiac fibroblasts mimicking heart failure phenotype
- Identify FGF2 signaling pathway as potential target for modulating apoptosis in cardiac pathology
- Investigate the roles of scleraxis and AMPKα1 in scar formation following myocardial infarction
- Show that the KATP channel opener KMUP-3 preserved cardiac function after myocardial infarction by enhancing the expression of NO synthase and restoring MMP-9/TIMP-1 balance
(Click to Enlarge) Human Cardiac Fibroblasts: HCF (L). HCF immunolabeled for FSP (green), nuclei are stained with PI (R).
Details
Tissue | Normal healthy human heart tissue |
QC | No bacteria, yeast, fungi, mycoplasma, virus |
Bioassay | Attach, spread, proliferate in Growth Med |
Cryovial | 500,000 HCF (1st passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO |
Kit | Cryovial frozen HCF (306A-05a, adult atrium; 306V-05a, adult ventricle; or 306-05f fetal) , Growth Medium (316-500), Subcltr Rgnt Kit (090K) |
Proliferating | Shipped in Gr Med, 2nd psg (flasks or plates) |
Doublings | At least 8 |
Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| Cryopreserved Human Cardiac Fibroblasts Total Kit, adult: 5x10^5 Cells (Adult), Medium & Subculture Reagents (See Details tab for specifics) | Size: 1 Kit | CAT.#: 306AK-05a | Price: $857.00 | |
| Cryopreserved Cardiac Fibroblasts, Atrium, (HCF)adult: Frozen HCF (5x10^5) | Size: 1 Cryovial | CAT.#: 306A-05a | Price: $690.00 | |
| Proliferating Cardiac Fibroblasts, Atrium, (HCF), adult: Actively growing, dividing cells in medium | Size: T-25 Flask | CAT.#: 307A-25a | Price: $690.00 | |
| Proliferating Cardiac Fibroblasts, Atrium, (HCF), adult: Actively growing, dividing cells in medium | Size: T-75 Flask | CAT.#: 307A-75a | Price: $880.00 | |
| Proliferating Cardiac Fibroblasts, Atrium, (HCF), adult: Actively growing, dividing cells in medium | Size: 24 Well | CAT.#: 307A-24Wa | Price: $880.00 | |
| Proliferating Cardiac Fibroblasts, Atrium, (HCF), adult: Actively growing, dividing cells in medium | Size: 96 Well | CAT.#: 307A-96Wa | Price: $1,000.00 | |
| Cryopreserved Human Cardiac Fibroblasts Total Kit, adult: 5x10^5 Cells (Adult), Medium & Subculture Reagents (See Details tab for specifics) | Size: 1 Kit | CAT.#: 306VK-05a | Price: $857.00 | |
| Cryopreserved Cardiac Fibroblasts, Ventricle, (HCF), adult: Frozen HCF (5x10^5) | Size: 1 Cryovial | CAT.#: 306V-05a | Price: $690.00 | |
| Proliferating Cardiac Fibroblasts, Ventricle, (HCF), adult: Actively growing, dividing cells in medium | Size: T-25 Flask | CAT.#: 307V-25a | Price: $690.00 | |
| Proliferating Cardiac Fibroblasts, Ventricle, (HCF), adult: Actively growing, dividing cells in medium | Size: T-75 Flask | CAT.#: 307V-75a | Price: $880.00 | |
| Proliferating Cardiac Fibroblasts, Ventricle, (HCF), adult: Actively growing, dividing cells in medium | Size: 24 Well | CAT.#: 307V-24Wa | Price: $880.00 | |
| Proliferating Cardiac Fibroblasts, Ventricle, (HCF), adult: Actively growing, dividing cells in medium | Size: 96 Well | CAT.#: 307V-96Wa | Price: $1,000.00 | |
| Cryopreserved Human Cardiac Fibroblasts Total Kit, adult: 5x10^5 Cells (Fetal), Medium & Subculture Reagents (See Details tab for specifics) | Size: 1 Kit | CAT.#: 306K-05f | Price: $857.00 | |
| Cryopreserved Cardiac Fibroblasts (HCF), fetal: Frozen HCF (5x10^5) | Size: 1 Cryovial | CAT.#: 306-05f | Price: $690.00 | |
| Proliferating Cardiac Fibroblasts (HCF), fetal: Actively growing, dividing cells in medium | Size: T-25 Flask | CAT.#: 307-25f | Price: $690.00 | |
| Proliferating Cardiac Fibroblasts (HCF), fetal: Actively growing, dividing cells in medium | Size: T-75 Flask | CAT.#: 307-75f | Price: $880.00 | |
| Proliferating Cardiac Fibroblasts (HCF), fetal: Actively growing, dividing cells in medium | Size: 24 Well | CAT.#: 307-24Wf | Price: $880.00 | |
| Proliferating Cardiac Fibroblasts (HCF), fetal: Actively growing, dividing cells in medium | Size: 96 Well | CAT.#: 307-96Wf | Price: $1,000.00 |
Related Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| HCF Growth Medium: All-in-one ready-to-use | Size: 500 ml | CAT.#: 316-500 | Price: $114.00 | |
| HCF Growth Medium Kit: Basal Medium and Growth Supplement sold together, bottled separately | Size: yields 500 ml | CAT.#: 316K-500 | Price: $124.00 | |
| HCF Basal Medium: Basal medium (contains no growth supplement). Add GS before use. | Size: 500 ml | CAT.#: 315-500 | Price: $74.00 | |
| HCF Growth Supplement: Added to Basal Medium to create Growth Medium | Size: 50 ml | CAT.#: 316-GS | Price: $66.00 |
Extended Family Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| Polyclonal Fibroblast Growth Factor 2 Rabbit Antibody: Polyclonal Fibroblast Growth Factor 2, FGF2 (bFGF), Rabbit Antibody | Size: 100 ul | CAT.#: CA0259 | Price: $302.00 | |
| Polyclonal Fibroblast Growth Factor 7, KGF, Rabbit Antibody: Polyclonal Fibroblast Growth Factor 7, KGF, Rabbit Antibody | Size: 100 ul | CAT.#: CA0853 | Price: $302.00 | |
| Rabbit Fibroblast Growth Factor 8 Antibody: Rabbit Fibroblast Growth Factor 8 Antibody | Size: 100 ul | CAT.#: CA1216 | Price: $302.00 | |
| Mouse Fibroblast Growth Factor Receptor 1 Antibody: Mouse Fibroblast Growth Factor Receptor 1 Antibody | Size: 100 ul | CAT.#: CP10102 | Price: $333.00 | |
| Polyclonal Fibroblast Growth Factor-Receptor 2 Antibody: Polyclonal Fibroblast Growth Factor-Receptor 2 Antibody | Size: 100 ul | CAT.#: CB4365 | Price: $333.00 | |
| Mouse Fibroblast Growth Factor Receptor Tyrosine Kinase 4 Antibody: Mouse Fibroblast Growth Factor Receptor Tyrosine Kinase 4 Antibody | Size: 100 ul | CAT.#: CP10103 | Price: $333.00 | |
| Rabbit Macrophage Migration Inhibitory Factor Antibody: Rabbit Macrophage Migration Inhibitory Factor Antibody | Size: 100 ul | CAT.#: CA1052 | Price: $302.00 | |
| Cyto-X Cell Counting Reagent: 500 tests | Size: 1 Bottle | CAT.#: 028-01 | Price: $160.00 | |
| Cyto-X Cell Counting Reagent Sample: 100 tests | Size: Sample | CAT.#: 028-S | Price: $41.00 | |
| Cytofect Fibroblast Transfection Kit (250 x 24-Wells): 250 x 24-Well Rxns | Size: 1 Kit | CAT.#: TF103K | Price: $465.00 | |
| Cytofect Fibroblast Transfection Sample Kit (25 x 24-Wells): 25 x 24-Well Rxns | Size: 1 Sample Kit | CAT.#: TF103KS | Price: $62.00 | |
| Human Fibroblast Growth Factor-21 (FGF-21): Human Fibroblast Growth Factor-21 | Size: 20 ug | CAT.#: RP1148-20 | Price: $194.00 | |
| Human Fibroblast Growth Factor-21 (FGF-21): Human Fibroblast Growth Factor-21 | Size: 100 ug | CAT.#: RP1148-100 | Price: $484.00 | |
| Human Fibroblast Growth Factor-21 (FGF-21): Human Fibroblast Growth Factor-21 | Size: 1000 ug | CAT.#: RP1148-1000 | Price: $3,175.00 | |
| Human Fibroblast Growth Factor-22 (FGF-22): Human Fibroblast Growth Factor-22 | Size: 20 ug | CAT.#: RP1068-20 | Price: $194.00 | |
| Human Fibroblast Growth Factor-22 (FGF-22): Human Fibroblast Growth Factor-22 | Size: 100 ug | CAT.#: RP1068-100 | Price: $624.00 | |
| Human Fibroblast Growth Factor-22 (FGF-22): Human Fibroblast Growth Factor-22 | Size: 1000 ug | CAT.#: RP1068-1000 | Price: $5,166.00 | |
| Human Fibroblast Growth Factor Acidic (FGF-1): Human Fibroblast Growth Factor-acidic | Size: 10 ug | CAT.#: RP1029-10 | Price: $81.00 | |
| Human Fibroblast Growth Factor Acidic (FGF-1): Human Fibroblast Growth Factor-acidic | Size: 50 ug | CAT.#: RP1029-50 | Price: $194.00 | |
| Human Fibroblast Growth Factor Acidic (FGF-1): Human Fibroblast Growth Factor-acidic | Size: 1000 ug | CAT.#: RP1029-1000 | Price: $1,561.00 | |
| Human FGF9 ELISA Kit: Human Fibroblast Growth Factor 9 ELISA Kit | Size: 96 Wells | CAT.#: CL0348 | Price: $457.00 | |
| Cardiac Fibroblast RNA (HCF RNA), Fetal: Total RNA prepared from Human Cardiac Fibroblasts, fetal | Size: 10 ug | CAT.#: 306-R10f | Price: $398.00 | |
| Cardiac Fibroblast RNA (HCF RNA), Fetal: Total RNA prepared from Human Cardiac Fibroblasts, fetal | Size: 25 ug | CAT.#: 306-R25f | Price: $796.00 | |
| Cardiac Fibroblast RNA (HCF RNA), Adult: Total RNA prepared from Human Cardiac Fibroblasts, adult | Size: 10 ug | CAT.#: 306-R10a | Price: $465.00 | |
| Cardiac Fibroblast RNA (HCF RNA), Adult: Total RNA prepared from Human Cardiac Fibroblasts, adult | Size: 25 ug | CAT.#: 306-R25a | Price: $930.00 | |
| Human Heart RNA: Total RNA prepared from human heart tissue | Size: 50 ug | CAT.#: 1H30-50 | Price: $158.00 | |
| Human Heart RNA: Total RNA prepared from human heart tissue | Size: 250 ug | CAT.#: 1H30-250 | Price: $595.00 | |
| Subculture Reagent Kit: 100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution | Size: 1 Kit | CAT.#: 090K | Price: $63.00 | |
| Human Fibroblast Growth Factor-4 (FGF-4): Human Fibroblast Growth Factor-4 | Size: 25 ug | CAT.#: RP1031-25 | Price: $194.00 | |
| Human Fibroblast Growth Factor-4 (FGF-4): Human Fibroblast Growth Factor-4 | Size: 100 ug | CAT.#: RP1031-100 | Price: $484.00 | |
| Human Fibroblast Growth Factor-4 (FGF-4): Human Fibroblast Growth Factor-4 | Size: 1000 ug | CAT.#: RP1031-1000 | Price: $3,175.00 | |
| Human Fibroblast Growth Factor 147 Basic (FGF-147 basic/FGF-2): Human Fibroblast Growth Factor-147-basic | Size: 10 ug | CAT.#: RP1028-10 | Price: $81.00 | |
| Human Fibroblast Growth Factor 147 Basic (FGF-147 basic/FGF-2): Human Fibroblast Growth Factor-147-basic | Size: 100 ug | CAT.#: RP1028-100 | Price: $317.00 | |
| Human Fibroblast Growth Factor 147 Basic (FGF-147 basic/FGF-2): Human Fibroblast Growth Factor-147-basic | Size: 1000 ug | CAT.#: RP1028-1000 | Price: $1,561.00 | |
| Human Fibroblast Growth Factor 154 Basic (FGF-basic 154 / FGF-2): Human Fibroblast Growth Factor-154-basic | Size: 10 ug | CAT.#: RP1146-10 | Price: $81.00 | |
| Human Fibroblast Growth Factor 154 Basic (FGF-basic 154 / FGF-2): Human Fibroblast Growth Factor-154-basic | Size: 100 ug | CAT.#: RP1146-100 | Price: $253.00 | |
| Human Fibroblast Growth Factor 154 Basic (FGF-basic 154 / FGF-2): Human Fibroblast Growth Factor-154-basic | Size: 1000 ug | CAT.#: RP1146-1000 | Price: $1,561.00 | |
| Human Granulocyte Macrophage Colony Stimulating Factor (GM-CSF): Human Granulocyte Macrophage-Colony Stimulating Factor | Size: 20 ug | CAT.#: RP1008-20 | Price: $194.00 | |
| Human Granulocyte Macrophage Colony Stimulating Factor (GM-CSF): Human Granulocyte Macrophage-Colony Stimulating Factor | Size: 100 ug | CAT.#: RP1008-100 | Price: $484.00 | |
| Human Granulocyte Macrophage Colony Stimulating Factor (GM-CSF): Human Granulocyte Macrophage-Colony Stimulating Factor | Size: 1000 ug | CAT.#: RP1008-1000 | Price: $3,444.00 | |
| Human Gamma-Interferon Inducible Protein 10 (IP-10 / CXCL10): Human gamma-Interferon Inducible Protein 10 | Size: 25 ug | CAT.#: RP1127-25 | Price: $194.00 | |
| Human Gamma-Interferon Inducible Protein 10 (IP-10 / CXCL10): Human gamma-Interferon Inducible Protein 10 | Size: 100 ug | CAT.#: RP1127-100 | Price: $484.00 | |
| Human Gamma-Interferon Inducible Protein 10 (IP-10 / CXCL10): Human gamma-Interferon Inducible Protein 10 | Size: 1000 ug | CAT.#: RP1127-1000 | Price: $3,175.00 | |
| Human Migration Inhibitory Factor (MIF): Human Migration Inhibitory Factor | Size: 25 ug | CAT.#: RP1153-25 | Price: $194.00 | |
| Human Migration Inhibitory Factor (MIF): Human Migration Inhibitory Factor | Size: 100 ug | CAT.#: RP1153-100 | Price: $484.00 | |
| Human Migration Inhibitory Factor (MIF): Human Migration Inhibitory Factor | Size: 1000 ug | CAT.#: RP1153-1000 | Price: $3,175.00 | |
| Human MIF ELISA Kit: Human Macrophage Migration Inhibitory Factor ELISA Kit | Size: 96 wells | CAT.#: CL0813 | Price: $511.00 | |
| Human GM-CSF, Animal-Free: Human Granulocyte Macrophage-Colony Stimulating Factor, Animal-Free | Size: 20 ug | CAT.#: RP1008AF-20 | Price: $213.00 | |
| Human GM-CSF, Animal-Free: Human Granulocyte Macrophage-Colony Stimulating Factor, Animal-Free | Size: 100 ug | CAT.#: RP1008AF-100 | Price: $533.00 | |
| Human GM-CSF, Animal-Free: Human Granulocyte Macrophage-Colony Stimulating Factor, Animal-Free | Size: 1000 ug | CAT.#: RP1008AF-1000 | Price: $3,788.00 | |
| Human FGF-147 basic, Animal-Free: Human Fibroblast Growth Factor-basic-147, Animal-Free | Size: 10 ug | CAT.#: RP1028AF-10 | Price: $89.00 | |
| Human FGF-147 basic, Animal-Free: Human Fibroblast Growth Factor-basic-147, Animal-Free | Size: 100 ug | CAT.#: RP1028AF-100 | Price: $347.00 | |
| Human FGF-147 basic, Animal-Free: Human Fibroblast Growth Factor-basic-147, Animal-Free | Size: 1000 ug | CAT.#: RP1028AF-1000 | Price: $1,717.00 | |
| Human FGF-basic 154, Animal-Free: Human Fibroblast Growth Factor-basic-154, Animal-Free | Size: 10 ug | CAT.#: RP1146AF-10 | Price: $89.00 | |
| Human FGF-basic 154, Animal-Free: Human Fibroblast Growth Factor-basic-154, Animal-Free | Size: 100 ug | CAT.#: RP1146AF-100 | Price: $276.00 | |
| Human FGF-basic 154, Animal-Free: Human Fibroblast Growth Factor-basic-154, Animal-Free | Size: 1000 ug | CAT.#: RP1146AF-1000 | Price: $1,717.00 |
Resources/Documents
Citations
Powered by BiozPublications
2017
Ross, G., T. Bajwa, S. Edwards, L. Emelyanova, F. Rivi, E. Holmuhamedov, P. Werner, F. Downey, A. Tajik and A. Jahangir. 2017. Enhanced store-operated Ca2+ influx and ORAI1 expression in ventricular fibroblasts from human failing heart. Biology Open Advance article
2016
Bagchi, R.., R. Wang, F. Jahan, J. Wigle and M. Czubryt. 2016. Regulation of scleraxis transcriptional activity by serine phosphorylation. J Molec & Cell Cardiol, doi:10.1016/j.yjmcc.2016.02.013.
Czubryt, M. 2016. Inhibition of collagen synthesis. Patent US 9238685 B2.
Hookway, T., J. Butts, E. Lee, H. Tang and T. McDevitt. 2016. Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny. Methods, 101:11-20.
Hung, C., C. Chou, C. Liao, Y. Lin, X. Wu, Y. Chang, Y. Chen, V. Wu, M. Su, Y. Ho, M. Chen, K. Wu and Y. Lin. 2016. Aldosterone Induces Tissue Inhibitor of Metalloproteinases-1 Expression and Further Contributes to Collagen Accumulation. Hypertension, 67:1309-1320.
Jonsson, M., R. Hartman, M. Ackers-Johnson, W. Tan, B. Lim, T. van Veen and R. Foo. 2016. A Transcriptomic and Epigenomic Comparison of Fetal and Adult Human Cardiac Fibroblasts Reveals Novel Key Transcription Factors in Adult Cardiac Fibroblasts. JACC: Basic to Translational Science, 7:590-602.
Nagpal, V., R. Rai, A. Place, S. Murphy, S. Verma, A. Ghosh and D. Vaughan. 2016. MiR-125b Is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis. Circulation, 133:291-301.
Rizvi, F., A. DeFranco, R. Siddiqui, U. Negmadjanov, L. Emelyanova, A. Holmuhamedov, G. Ross, Y. Shi, E. Holmuhamedov, D. Kress, A. Tajik and A. Jahangir. 2016. Chamber-specific differences in human cardiac fibroblast proliferation and responsiveness toward simvastatin. Am J Physiol – Cell Physiol, 311:C330-339.
Sundaresan, N., S. Bindu, V. Pillai, S. Samant, Y. Pan, J. Huang, M. Gupta, R. Nagalingam, D. Wolfgeher, E. Verdin and M. Gupta. 2016. SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β. Mol Cell Biol, 36:678-692.
2015
Momtahan, N., N. Poornejad, J. Struk, A. Castleton, B. Herrod, B. Vance, J. Eatough, D. Roeder, P. Reynolds, and D. Cook. 2015. Automation of Pressure Control Improves Whole Porcine Heart Decellularization. Tissue Engineering Part C: Methods, doi:10.1089/ten.TEC.2014.0709.
Philip, J., A. Razzaque, M. Han, J. Li, T. Thecanat, X. Xu, and S. Akhter. 2015. Regulation of Mitochondrial Oxidative Stress by β-arrestins in Cardiac Fibroblasts. Disease Models & Mechanisms. doi: 10.1242/dmm.019968.
Tomita, K., M. Takashina, N. Mizuno, K. Sakata, K. Hattori, J. Imura, W. Ohashi, and Y. Hattori. 2015. Cardiac fibroblasts: contributory role in septic cardiac dysfunction. Journal of Surgical Research, 193:874–887.
2014
Ichiki, T., J. Schirger, B. Huntley, F. Brozovich, J. Maleszewski, S. Sandberg, S. Sangaralingham, S. Park, and J. Burnett. 2014. Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: Regulation and therapeutic implications. J Molecular and Cellular Cardiol, 75:199-205.
Li, J., J. Philip, X. Xu, T. Theccanat, M. Razzaque, and S. Akhter. 2014. β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling. JMCC, 76:73-83.
Noppe, G., C. Dufeys, P. Buchlin, N. Marquet, D. Castanares-Zapatero, M. Balteau, N. Hermida, C. Bouzin, H. Esfahani, B. Viollet, L. Bertrand, J. Balligand, J. Vanoverschelde, C. Beauloye, and S. Horman. 2014. Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1. Journal of Molecular and Cellular Cardiology, 74:32–43.
2013
Yue, Z., Y. Zhang, J. Xie, J. Jiang, and L. Yue. 2013. Transient Receptor Potential (TRP) channels and cardiac fibrosis. Current topics in medicinal chemistry. 13:270-282
2012
Bagchi, R.A., and M.P. Czubryt. 2012. Synergistic roles of scleraxis and Smads in the regulation of collagen 1α2 gene expression. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1823:1936-1944.
Czubryt, M. 2012. Inhibition of collagen synthesis. Patent Application US 20140288003 A1.
Savvatis, K., S. van Linthout, K. Miteva, K. Pappritz, D. Westermann, J.C. Schefold, G. Fusch, A. Weithäuser, U. Rauch, P.-M. Becher, K. Klingel, J. Ringe, A. Kurtz, H.-P. Schultheiss, and C. Tschöpe. 2012. Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis. PloS one. 7:e41047.
2011
Bogaard, H.J., S. Mizuno, A.A.A. Hussaini, S. Toldo, A. Abbate, D. Kraskauskas, M. Kasper, R. Natarajan, and N.F. Voelkel. 2011. Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats. American journal of respiratory and critical care medicine. 183:1402-1410.
Chen, I. 2011. Use of kmup-3 for myocardial infarction. Patent Application US 20120095013 A1.
Czubryt, M. 2011. Modulation of scleraxis using a dominant negative scleraxis mutant with a basic dna-binding domain deletion. Patent Application US 20130123198 A1.
D'Souza, K.M., R. Malhotra, J.L. Philip, M.L. Staron, T. Theccanat, V. Jeevanandam, and S.A. Akhter. 2011. G Protein-coupled Receptor Kinase-2 Is a Novel Regulator of Collagen Synthesis in Adult Human Cardiac Fibroblasts. Journal of Biological Chemistry. 286:15507-15516.
Liu, C.P., J.L. Yeh, B.N. Wu, C.Y. Chai, I.J. Chen, and W.T. Lai. 2011. KMUP‐3 attenuates ventricular remodelling after myocardial infarction through eNOS enhancement and restoration of MMP‐9/TIMP‐1 balance. Brit. J. Pharmacol. 162:126-135.
Ma, X. 2011. Studies on signals mediating or preventing the intracrine induction of chromatin compaction and cell death by high molecular weight fibroblast growth factor 2. University of Manitoba, PhD dissertation.
Miteva, K., M. Haag, J. Peng, K. Savvatis, P.M. Becher, M. Seifert, K. Warstat, D. Westermann, J. Ringe, M. Sittinger, H.-P. Schultheiss, C. Tschöpe, and S. Van Linthout. 2011. Human Cardiac-Derived Adherent Proliferating Cells Reduce Murine Acute Coxsackievirus B3-Induced Myocarditis. PloS one. 6:e28513.
Silberbach, M., C. Roberts, and N. Airhart. 2011. Methods of screening using a natriuretic peptide receptor. Patent US 7943296 B2.
Silberbach, M., C. Roberts, and N. Airhart. 2011. Natriuretic peptide related fragment in cardiovascular disease. Patent Application US 20110218230 A1.
2010
Peng, H., O.A. Carretero, E.L. Peterson, and N.-E. Rhaleb. 2010. Ac-SDKP inhibits transforming growth factor-β1-induced differentiation of human cardiac fibroblasts into myofibroblasts. American J. of Physiology 298:H1357-H1364.
2007
Wang, Y.-J., M.-W. Lin, S.-N. Wu, and R.J. Sung. 2007. The activation by estrogen receptor agonists of the BKCa-channel in human cardiac fibroblasts. Biochemical pharmacology. 73:1347-1357. Young, E.F., and E.E. Marcantonio. 2007. A Novel Subcellular Collagen Organization Process Visualized by Total Internal Reflection Fluorescence Microscopy. Cell Communication and Adhesion. 14:169-180.
2006
Wang, Y.-J., R. Sung, M.-W. Lin, and S.-N. Wu. 2006. Contribution of BKCa-Channel Activity in Human Cardiac Fibroblasts to Electrical Coupling of Cardiomyocytes-Fibroblasts. J Membrane Biol. 213:175-185.
2005
Dubey, R.K., E.K. Jackson, D.G. Gillespie, M. Rosselli, F. Barchiesi, A. Krust, H. Keller, L.C. Zacharia, and B. Imthurn. 2005. Cytochromes 1A1/1B1-and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast. Journal of Clinical Endocrinology & Metabolism. 90:247-255.