Top: Western Blot detection of BDH1 proteins in HepG2 and NIH3T3 cell lysates using BDH1 Antibody. Bottom: This antibody stains paraffin-embedded colon cancer tissue in immunohistochemical analysis.
Anti-BDH1: Mouse 3-Hydroxybutyrate Dehydrogenase, Type 1 Antibody
Mouse 3-Hydroxybutyrate Dehydrogenase, Type 1 Antibody: Mouse 3-Hydroxybutyrate Dehydrogenase, Type 1 Antibody
Size: 100 ul
Price: $413.00
Description
BACKGROUNDÂ BDH1 (3-hydroxybutyrate dehydrogenase, type 1) is a member of the short-chain dehydrogenase/reductase family. This protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. It catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism.1
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REFERENCESÂ Â
1. Marks, A.R. et al: J. Biol. Chem. 267:15459-63, 1992
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Products are for research use only. They are not intended for human, animal, or diagnostic applications.
Details
| Cat.No.: | CP10023 |
| Antigen: | Purified recombinant human BDH1-Fc fusion protein expressed in 293 cells. |
| Isotype: | Mouse IgG1 |
| Species & predicted species cross- reactivity ( ): | Human, Mouse |
| Applications & Suggested starting dilutions:* | WBÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 1:500 – 1:2000 IPÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 1:25 – 1:50 IHCÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 1:200 ICCÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â n/d FACSÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â n/d |
| Predicted Molecular Weight of protein: | 45Â kDa |
| Specificity/Sensitivity: | Detects endogenous BDH1 proteins in normal cell lysates without cross-reactivity with other related proteins. |
| Storage: | Store at -20°C, 4°C for frequent use. Avoid repeated freeze-thaw cycles. |
*Optimal working dilutions must be determined by end user.