Anti-KLHL25: Mouse KLHL25 Antibody
Mouse KLHL25 Antibody: Mouse KLHL25 Antibody
Size: 100 ul
Price: $413.00
Description
KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.3
2. Perez-Torrado, R. et al: BioEssays 28: 1194–1202, 2006
3. Kruger, A. et al: Genome Biol. 8:R229, 2007
Details
Cat.No.: | CP10340 |
Antigen: | raised against recombinant human KLHL25 fragments expressed in E. coli. |
Isotype: | Mouse IgG1 |
Species & predicted species cross- reactivity ( ): | Human, Mouse, Rat |
Applications & Suggested starting dilutions:* | WB 1:1000 IP n/d IHC n/d ICC n/d FACS n/d |
Predicted Molecular Weight of protein: | 65 kDa |
Specificity/Sensitivity: | Detects endogenous KLHL25 proteins without cross-reactivity with other family members. |
Storage: | Store at -20°C, 4°C for frequent use. Avoid repeated freeze-thaw cycles. |
*Optimal working dilutions must be determined by end user.