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IFNα2a: Human Interferon-alpha 2a

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BACKGROUND  Interferon-alpha 2a (IFN-α2a) is a type I interferon made by leukocytes during viral infection.  The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α2a.  IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies.  The IFN-α2a variant differs from IFN-α2b by one amino acid.

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