Laminin Standard Curve: Using the Rat Laminin ELISA Kit, O.D. data was graphed against Laminin protein concentration. The TMB reaction was incubated at 37°C for 12 min.
Laminin ELISA Kit, Rat
Rat Laminin ELISA Kit: Rat Laminin ELISA Kit
Size: 96 wells
Price: $752.00
Description
In mammals they play at least three essential roles.3 First, they are major structural elements of basal laminae (BLs), forming one of two self-assembling networks (the other is composed of the collagens IV) to which other glycoproteins and proteoglycans of the BL attach. Second, they interact with cell surface components such as dystroglycan to attach cells to the extracellular matrix. Third, they are signaling molecules that interact with cellular receptors such as the integrins to convey morphogenetically important information to the cell’s interior. For example, laminin promotes myogenesis in skeletal muscle, outgrowth of neurites from central and peripheral neurons, and mesenchymal to epithelial transitions in kidney. Through these interactions, laminins critically contribute to cell differentiation, cell shape and movement, maintenance of tissue phenotypes, and promotion of tissue survival. Recent advances in the characterization of genetic disruptions in humans, mice, nematodes and flies have revealed developmental roles for the different laminin subunits in diverse cell types, affecting differentiation from blastocyst formation to the post-natal period.
2. Martin, G.R. & Timpl, R.: Ann. Rev. Cell Biol. 3:57-85, 1987
3. Mercurio, A.M.: Trends Cell Biol. 5:419-23, 1995
Details
| Cat.No.: | CL0435 |
| Target Protein Species: | Rat |
| Range: | 156pg/ml – 10000pg/ml |
| Specificity: | No detectable cross-reactivity with any other cytokines |
| Storage: | Store at 4°C. Use within 6 months. |
