Product Sheet RP2027
Product Sheet RP2027AF
Description
BACKGROUND Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-beta family of proteins signal through serine/threonine kinase receptors. TGF-beta isoforms (TGF-beta1, -beta2, and –beta3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-beta3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-beta3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.
Recombinant Mouse Transforming Growth Factor Beta-3 is a non-glycosylated protein dimer, containing 113/226 amino acids and having a molecular mass of 12.9/25.7 kDa.
Products are for research use only. They are not intended for human, animal, or diagnostic applications.
Details
Cat. No.:
RP2027 / RP2027AF
Source:
E. coli
Physical Appearance:
In solution
Formulation:
10 mM acetic acid and 20% Ethanol at a concentration of 0.25 mg/mL
Stability:
Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
Protein Content and Purity determined by:
• UV spectroscopy at 280 nm.
• RP-HPLC calibrated against a known standard.
• Quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
Endotoxin Level:
Endotoxin level, as measured by LAL analysis, is <0.01ng/ug or <0.1EU/ug.
Biological Activity:
The activity is measured by the dose-dependent inhibition of IL-4-induced HT-2 cell proliferation, Bioactivity Acceptance Criteria ED50 at 1 ng/mL.
AA Sequence:
MALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
Animal Component-Free
This product is produced with no animal derived raw products. All processing and handling employs animal free equipment and animal free protocols.
Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| Mouse Transforming Growth Factor Beta-3 (TGF-beta 3): Mouse Transforming Growth Factor Beta-3 | Size: 10 ug | CAT.#: RP2027-10 | Price: $195.00 | |
| Mouse Transforming Growth Factor Beta-3 (TGF-beta 3): Mouse Transforming Growth Factor Beta-3 | Size: 100 ug | CAT.#: RP2027-100 | Price: $687.00 | |
| Mouse Transforming Growth Factor Beta-3 (TGF-beta 3): Mouse Transforming Growth Factor Beta-3 | Size: 1000 ug | CAT.#: RP2027-1000 | Price: $5,640.00 | |
| Mouse TGF-beta 3, Animal-Free: Human Transforming Growth Factor-beta-3 | Size: 10 ug | CAT.#: RP2027AF-10 | Price: $215.00 | |
| Mouse TGF-beta 3, Animal-Free: Human Transforming Growth Factor-beta-3 | Size: 100 ug | CAT.#: RP2027AF-100 | Price: $758.00 | |
| Mouse TGF-beta 3, Animal-Free: Human Transforming Growth Factor-beta-3 | Size: 1000 ug | CAT.#: RP2027AF-1000 | Price: $6,110.00 |