 Cryopreserved Rat Macrophages: RMcp (top) cultured for 2 days. Bottom: DiI-Ac-LDL (in red) uptake in cryopreserved RMcp cultured for 3 days (R). Cryopreserved RMcp cultured for 4 days stained for CD11b/c (in green) and DAPI (in blue) (R).
Rat Macrophages: RMcp
Description
Rat Macrophages (RMcp)Â are derived from bone marrow of normal rats by standardized methods. When revived and plated and cultured under recommended conditions, RMcp form adherent culture. Macrophages and their precursors, monocytes, belong to the white blood cell family and engulf and digest cellular debris and foreign pathogens through phagocytosis. They play a central role in modulating the immune system by antigen presentation, recruiting and instructing other immune cells. Due to their great anatomical and functional diversity, macrophages have been widely used in research to study inflammation, wound healing, development, homeostatsis, degeneration, cancer progression and metastasis. Characterization:Â RMcp stain positive for F4/80 and CD11b/c, and uptake DiI-Ac-LDL
Details
| Tissue | Normal healthy Rat bone marrow |
|---|---|
| QC | No bacteria, yeast, fungi, mycoplasma |
| Character | Positive for F4/80 and CD11b/c |
| Bioassay | Plate, spread on CC ware & uptake DiI-Ac-LDL |
| Cryovial | 1M RMcp frozen in Macrophage & Microglia Cell Freezing Med (043-50) |
| Kit | Cryovial Frozen RMcp (R8818-10a), Culture Medium Kit (R620K-100) |
| Doublings | N/A - Blood cells don't proliferate in vitro |
| Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
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