Canine Endothelial Cell Media, formulated specifically for vascular cells isolated from dog tissue.
Canine Endothelial Cell Media
Canine EC Growth Medium: All-in-one ready-to-use
Type: Growth Medium
Size: 500 ml
Price: $154.00
Description
Canine Endothelial Cell Media are specialized growth formulations designed to support the attachment, proliferation, and functional maintenance of primary canine vascular endothelial cells in vitro. Endothelial cells line the interior surface of blood vessels throughout the circulatory system, where they form a dynamic barrier that regulates vascular tone and permeability, nutrient and metabolite exchange, and signaling pathways involved in vascular inflammation and hemostasis.
In canine research models, endothelial cells isolated from vascular beds such as aorta, coronary, pulmonary, and microvascular tissues provide valuable primary cell systems for studying cardiovascular physiology and disease mechanisms. These cultures help researchers investigate processes central to vascular biology, including angiogenesis, endothelial activation, leukocyte recruitment, and barrier-related responses — pathways that are also relevant to conditions such as atherosclerosis, thrombosis, and tumor microenvironment biology. By enabling the growth of healthy, proliferative endothelial cultures, Canine Endothelial Cell Media support experimental systems used for treatment evaluation and mechanistic cell biology studies in dogs.
In research and translational workflows, Canine Endothelial Cell Media provide a tailored, nutrient-rich cell culture environment supplemented with endothelial growth-supporting cues, including growth factors such as VEGF and bFGF, to sustain endothelial morphology and metabolic activity across serial passages. Endothelial cultures maintained in these media are commonly assessed using canonical endothelial markers (for example, CD31/PECAM-1 and von Willebrand factor, vWF) and functional readouts relevant to endothelial function, including DiI-Ac-LDL uptake and tube formation assays for angiogenic behavior. For population-level verification and analysis, researchers may use flow cytometry to evaluate marker expression and culture consistency.
Canine Endothelial Cell Media help provide a standardized endothelial cell culture platform for veterinary and comparative cardiovascular research. By supporting reproducible proliferation and preservation of primary endothelial phenotype, these media contribute to data generation across studies of endothelial dysfunction, inflammatory signaling, and therapeutic application strategies — advancing investigations that connect canine models to broader human vascular medicine.
Medium carefully optimized for the characteristics and requirements unique to Canine Endothelial Cells. Attention to detail ensures ideal cell health, viability, performance, physiology, morphology, consistency and data.
Use with:
Details
CAI media are tested for sterility in order to confirm no bacteria, yeast or fungi contaminate the solutions. The products undergo further quality control for correct pH, osmolality and lack of endotoxins. A panel of different bioassays affirm the media sustain a proper environment for expected cell-type-specific culture, growth, plating, karyotype, physiology, morphology, viability, population doublings, surface markers, cryopreservation, differentiation and/or induction.
Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.
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