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Human Hair Follicle Dermal Papilla Cell Media

HFDPC Growth Medium: All-in-one ready-to-use

Type: Growth Medium
Size: 500 ml

CAT. #: 611-500

Price: $147.00

Quantity

Description

Human Hair Follicle Dermal Papilla Cell Media is a specialized primary cell culture media designed to support the culture of human hair follicle dermal papilla cells (HFDPC), also sometimes called DP cells, and to help maintain DP cell health and activity in vitro. Dermal papilla cells are fibroblasts located in the hair follicle’s dermal sheath region and are widely studied as key regulators of hair follicle behavior across the hair cycle, including the anagen phase (growth phase) and transitions toward telogen and the telogen phase associated with follicular slowdown. Because dermal papilla cells provide instructive signals to neighboring epithelial populations, they are central to research on hair follicle biology, including hair follicle precursors and adult dermal stem cells, and to investigations of hair follicle regeneration after periods of follicular decline. These roles also make dermal papilla cells relevant to studies addressing hair loss.

In the body, dermal papilla cells reside at the base of the hair follicle within the dermal sheath and coordinate signaling with surrounding keratinocyte populations that contribute to formation and growth of the hair shaft. Their functional importance includes supporting follicle progression during the growth phase, influencing the molecular and cellular events that accompany hair cycle stage changes, and helping regulate whether the follicle can resume growth rather than remain in or progress through telogen. In vitro, Human Hair Follicle Dermal Papilla Cell Media helps sustain DP cells in a consistent state, which supports experiments that probe how changes in culture environment affect DP cell activity and the downstream hair follicle response.

Human Hair Follicle Dermal Papilla Cell Media is used by researchers to establish reproducible DP cell cultures for mechanistic studies of hair growth control and the biology of cycling follicles. Cultured DP cells are used to evaluate how candidate compounds, biologics, or signaling pathway perturbations influence DP cell behavior and related hair follicle outcomes — supporting assays that measure DP cell responses over time and that can be linked to transitions from telogen back toward anagen. Because DP cell behavior is sensitive to culture conditions, the availability of defined culture-friendly formulations and consistent media performance supports researchers in generating comparable results across experiments, including studies focused on the cellular basis of hair follicle regeneration and the drivers of hair loss.

Within hair research programs, the medium is typically supplied in practical formats and maintained under sterile conditions to help minimize risk from microbial contaminants such as bacteria, fungi, and mycoplasma. Researchers may also use related reagents and cell culture workflows to maintain culture continuity, support standardized DP cell number handling (including tracking DP cell number and maintaining DP cells), and integrate DP cell cultures with other follicular cell types such as keratinocytes and hair follicle precursors. This enables downstream research focused on sensitive processes such as controlling culture-induced variability—important for robust scientific outcomes in adult hair biology and regenerative medicine.

Medium carefully optimized for the characteristics and requirements unique to Human Hair Cells.  Attention to detail ensures ideal cell health, viability, performance, physiology, morphology, consistency and data.

Details

CAI media are tested for sterility in order to confirm no bacteria, yeast or fungi contaminate the solutions.  The products undergo further quality control for correct pH, osmolality and lack of endotoxins. A panel of different bioassays affirm the media sustain a proper environment for expected cell-type-specific culture, growth, plating, karyotype, physiology, morphology, viability, population doublings, surface markers, cryopreservation, differentiation and/or induction.
Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.
MSDS 610-500

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MSDS 611-500

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MSDS 611F2-500

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MSDS 611F-500

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MSDS 611-GS

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MSDS 611K-500

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