Human Mononuclear Cells: HMNC. Peripheral Blood versions also commonly known as “PBMC.”
Human Mononuclear Cells from Bone Marrow: HMNC-BM
Description
Human Mononuclear Cells derived from Bone Marrow (HMNC-BM) are widely used in research and clinical applications every day, and provide a useful tool for studying various aspects of pathology and biology in vitro. Cell Applications HMNC are cryopreserved immediately after isolation.
HMNC-BM are important tools for studies in:
- Immunology (including auto-immune disorders), infectious disease, hematological malignancies, vaccine development, transplant immunology
- High-throughput screening
- Neovascularization to improve limb ischemia and in cell therapy to repair ischemic and infracted myocardium.
- Human body defense mechanisms critical in the immune system to fight bacterial and viral infections, and function as immune surveillance network to kill tumor cells.
- The secretion of cytokines to regulate immune response and inflammation
- Biological effects on tissue and organs.
- Chemokine effects on adipocytes and muscles
Details
| Tissue | Normal healthy human bone marrow | |
|---|---|---|
| QC | No HIV-1, Hepatitis B or Hepatitis C Viruses | |
| Cryovial | 5M HMNC-BM frozen right after isolation in FzM w/ 45% FBS, 10% DMSO | |
| Kit | Cryovial Frozen HMNC-BM (690BM-50a), Cltr Med (615-250) | |
| Doublings | N/A – Blood cells don’t proliferate in vitro |
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