Mouse Microglia: MMcg
Description
Mouse Microglia (MMcg) are primary mouse microglia derived from day 1 postnatal CD1 mouse brains. When revived and plated and cultured under recommended conditions, MMcg form adherent culture. Microglia, originated from the hematopoietic stem cells in bone marrow, are the resident macrophages in the central nervous system (CNS) which is separated from the rest of the body due to the presence of blood-brain barrier. Microglia actively survey the surrounding area and respond by scavenging damaged neural cells, plaques, and infectious agents. Due to their functions in immune response and maintaining homeostasis in the CNS, microglia have been implicated in neurodevelopment, CNS plasticity and repair, neuroinflammation, aging and neurodegeneration, neuropathic pain, and infections. Characterization: MMcg stain positive for F4/80, and uptake DiI-Ac-LDL
Details
| Tissue | Normal, healthy mouse brain | |
|---|---|---|
| QC | No bacteria, yeast, fungi, mycoplasma | |
| Character | Positive for F4/80Â | |
| Bioassay | Plate, spread on CC ware &Â uptake DiI-Ac-LDL | |
| Cryovial | 1M MMcg frozen in Microglia Cell Freezing Med (043-50) | |
| Kit | Cryovial Frozen MMcg (M8816K-10n), Microglia Cltr Med Kit (M619K-100) | |
| Doublings | N/A | |
| Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
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