Rat Lung Fibroblasts: RLF. Â Isolated directly from rodent pulmonary tissue.
Rat Lung Fibroblasts: RLF
Description
Rat Lung Fibroblasts (RLF) from Cell Applications, Inc. have been used to demonstrate that exaggerated (compared to adults) NF-κB activation in neonates in response to hyperoxia is mediated by phosphorylation of IκBα on Tyr42. They were also used to elucidate melatonin effects and signaling pathway and served as a control in studies investigating epithelial-mesenchimal transition as the source of myofibroblasts responsible for idiopathic pulmonary fibrosis.
Details
| Tissue | Normal healthy Sprague Dawley rat lung | |
|---|---|---|
| QC | No bacteria, yeast, fungi, mycoplasma | |
| Character | Positive for fibroblast surface protein | |
| Bioassay | Attach, spread, proliferate in Growth Med | |
| Cryovial | 500,000 RLF (2nd passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO | |
| Kit | Cryovial frozen RLF (R506-05a/-05n), Grwth Med (R116-500), Subcltr Rgnt Kit (090K) | |
| Proliferating | Shipped in Gr Med, 3rd psg (flasks or plates) | |
| Doublings | At least 10 | |
| Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
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