Human Internal Thoracic Endothelial Cells: HITAEC (L) immunolabeled for vWF (green) and CD31/PECAM (red) (M). Nuclei visualized with PI (red) (R).
Human Internal Thoracic Artery Endothelial Cells: HITAEC
Description
Human Internal Thoracic Artery Endothelial Cells (HITAEC) from Cell Applications, Inc. have been used to
- Investigate how oral pathogens travel through the body by infecting dendritic cells and inducing them to migrate through endothelial layers by causing upregulation of CXCR4
- Identify genes that make Human Internal Thoracic Arteries resistant to atherosclerosis
Additionally, HITAEC and HCAEC (also obtained from Cell Applications, Inc. but derived from the athero-prone human coronary arteries) were subjected to microarray analysis. Twenty-nine genes were found to be expressed differently between HITAEC and HCAEC; one of them (TES) was shown to be downregulated in patients with coronary artery disease, resulting in increased monocyte adhesion, endothelial cell motility and transendothelial migration of monocytes.
Details
| Tissue | Normal healthy human mammary artery | |
|---|---|---|
| QC | No bacteria, yeast, fungi, mycoplasma, virus | |
| Character | Factor VIII-related Ag & DiI-Ac-LDL uptake | |
| Bioassay | Attach, spread, proliferate in Growth Med | |
| Cryovial | 500,000 HITAEC (2nd psg) frozen in Basal Medium w/ 10% FBS, 10% DMSO | |
| Kit | Cryovial frozen HITAEC (308-05a), Growth Medium (212-500), Subculture Rgnt Kit (090K) | |
| Proliferating | Shipped in Gr Med, 3rd psg (flasks or plates) | |
| Doublings | At least 10 | |
| Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
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