Human MesoEndo Endothelial Cell Media, with components and supplements optimized for the culture of numerous arterial endothelial cell types, including Brachiocephalic, Carotid, Coronary, Internal Thoracic (Mammary), Subclavian and Umbilical.
Human MesoEndo Endothelial Cell Media
Human Meso Endo Growth Medium: All-in-one ready-to-use
Type: Growth Medium
Size: 500 ml
Price: $159.00
Description
Human MesoEndo Endothelial Cell Media is an endothelial cell growth medium formulated to support the culture of human endothelial cell types derived from mid-sized blood vessels, enabling researchers to maintain endothelial cell phenotype, physiology, morphology, and surface marker expression in a consistent cell culture medium environment. It is used with primary cells from vascular sources and is particularly suited to endothelial cells isolated from human cells associated with the arterial circulation, including Brachiocephalic, Carotid, Coronary, Internal Thoracic (Mammary), Subclavian, and Umbilical artery endothelial cell populations. In vivo, endothelial cells form the inner lining of blood vessels and regulate vascular functions such as barrier properties, leukocyte interaction, and growth-factor–dependent signaling, making them central to studies of vascular homeostasis and disease.
This media is supplied as a complete culture system with defined cell culture supplements and serum-supported or serum-compatible formulations, assembled for use as a growth medium that promotes endothelial cell health and viability during routine expansion and experimental workflows. By providing a standardized endothelial specific culture environment, Human MesoEndo Endothelial Cell Media supports cell biologics and other endothelial-focused research applications that rely on stable, well-characterized cultured cells. Researchers use endothelial cultures maintained under these optimized conditions to generate data for cell based assays, including experiments where endothelial function is challenged by inflammatory cues, metabolic stress, or pro-angiogenic signals, and to support co-culture and mechanistic studies linking vascular biology to epithelial or immune-associated processes (including investigations that incorporate immune cells and epithelial cells).
In translational research contexts, endothelial cell culture also supports genetic and functional perturbations. For example, endothelial cultures grown in this medium can be used in studies involving endothelial-targeted viral delivery, including endothelial specific adenoviral overexpression, and can facilitate experiments in which researchers track reporter populations (e.g., gfp expressing cells) or examine phenotypic responses of stable cells following transduction. Such approaches are frequently applied to tumor endothelial cell culture and related vascular remodeling studies, where endothelial behavior contributes to tumor progression and therapeutic response. The same culture platform can also be adapted for comparative experiments that include other species’ vascular cells — such as mouse cells and rat primary cells — using a consistent endothelial cell culture setup to evaluate conserved versus species-specific responses in mouse tissues and rat tissues contexts.
Overall, Human MesoEndo Endothelial Cell Media is intended to help researchers achieve reproducible endothelial culture performance for human vascular studies, while also serving as a practical foundation for broader experimental design. Depending on the project, it may be used alongside additional cell culture reagents to maintain endothelial cells during recovering periods after isolation or cryopreservation, support experiments using culture animal primary cells (including canine primary cells and porcine primary cells where applicable), or enable integrated workflows in which endothelial cells are compared with other circulating or tissue-derived primary human cells. This helps create a reliable basis for downstream molecular and functional assays using defined culture conditions and consistent cell culture protocols for endothelial-focused scientific investigations.
Medium carefully optimized for the characteristics and requirements unique to Human Endothelial Cells. Use this medium with mid-sized blood vessels. Attention to detail ensures ideal cell health, viability, performance, physiology, morphology, consistency and data.
Use with:
- Brachiocephalic Artery Endothelial Cells: HBcAEC
- Carotid Artery Endothelial Cells: HCtAEC
- Coronary Artery Endothelial Cells: HCAEC
- Internal Thoracic (Mammary) Artery Endothelial Cells: HITAEC
- Subclavian Artery Endothelial Cells: HScAEC
- Umbilical Artery Endothelial Cells: HUAEC
Head-to-Head Comparison Peer-Reviewed Article and Video
A recent peer-reviewed article published in Histochemistry and Cell Biology performed a head-to-head comparison of 7 leading cell culture media brands. Based on their results, the authors concluded the following in the publication’s Discussion:
“Fastest colony outgrowth and most colonies occurred in Cell Applications medium.”
See the video below:
Details
CAI media are tested for sterility in order to confirm no bacteria, yeast or fungi contaminate the solutions. The products undergo further quality control for correct pH, osmolality and lack of endotoxins. A panel of different bioassays affirm the media sustain a proper environment for expected cell-type-specific culture, growth, plating, karyotype, physiology, morphology, viability, population doublings, surface markers, cryopreservation, differentiation and/or induction.
Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.
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