Human Astrocytes (HA) (L). HA immunolabeled with anti-GFAP antibodies (green); nuclei are counterstained with DAPI (blue) (R).
Human Astrocytes: HA
Description
Human astrocytes (HA) are derived from human cerebral cortex. Astrocytes are the most abundant cells in the central nervous system where they perform many functions, such as providing mechanical support and nutrients to neurons and removal of wastes from neurons; providing signaling to endothelial cells; regulating neurogenesis and controlling synaptic function. As the recognition of the importance of astrocytes in nervous system is increasing, HA serve as a useful in vitro model for exploring the diversity of astrocytes functions.
Human Astrocytes from Cell Applications, Inc. have been used to:
- Investigate aberrant gene expression.
- Reveal that CBX6 overexpression inhibits proliferation of glyoblastoma cells and
- Demonstrate the role of epigenetics in glyioblastoma malignancy.
- Investigate choline uptake system in normal and glioblastoma cells with the hope to improve tomography imaging in glioblastoma patients
Characterization:Â Stained positive for GFAP
Details
| Tissue | Normal healthy Human brain | |
|---|---|---|
| QC | No bacteria, yeast, fungi, mycoplasma, virus | |
| Character | Positive for GFAP | |
| Bioassay | Attach, spread, proliferate in Growth Medium | |
| Cryovial | 500,000 HA (2nd passage) frozen in Basal Medium w/10% FBS, 10% DMSO | |
| Kit | Cryovial frozen HA (882A-05), Growth Medium (821-500), Subculture Rgnt Kit (090K) | |
| Proliferating | Shipped in Gr Med, 3rd psg (flasks or plates) | |
| Doublings | At least 10 for fetal, at least 8 for adult. | |
| Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
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