Top: Human Tracheal Epithelial Cells: HTEpC (L). HTEpC immunolabeled with an anti-CK18 antibody (R). Bottom: HTEpC (L) transfected with GFP plasmid DNA using the Cytofect™ Epithelial Cell Transfection Kit (R).
Human Tracheal Epithelial Cells: HTEpC
Description
Human Tracheal Epithelial Cells (HTEpC) provide a useful model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, pulmonary diseases and smoking. Note that Cell Applications, Inc. offers HTEpC obtained from healthy donors, as well as from asthma patients.
HTEpC from Cell Applications, Inc. have been used in a study investigating the role of goblet cell hyperplasia, possibly mediated by the expression of SPDEF, to the pathogenesis of chronic pulmonary diseases.
Characterization: Morphology consistent with epithelial origin, and positive for epithelial cell marker cytokeratin 18
Details
| Tissue | Surface epithelium of normal healthy human trachea | |
|---|---|---|
| QC | No bacteria, yeast, fungi, mycoplasma, virus | |
| Bioassay | Attach, spread, proliferate in Growth Medium | |
| Cryovial | 500,000 HTEpC (1st passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO | |
| Kit | Cryovial frozen HTEpC (504-05a), Growth Medium (511-500), Subcltr Rgnt Kit (090K) | |
| Proliferating | Shipped in Gr Med, 2nd psg (flasks or plates) | |
| Doublings | At least 16 | |
| Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
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