Description
The 3D Airway Model is a highly physiological, three-dimensional cellular system of Human Bronchial Epithelial Cells (HBEpC). The model facilitates in vitro examination of epithelial function and disease, including airway infections, tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries. Other investigations utilizing the Airway Model include mechanical and oxidative stress, inflammation, pulmonary diseases and smoking. The cells are grown and differentiated into a pseudostriated epithelium on PCF sitting inserts with a liquid/air interface. Contact us for more information.
(Click to Enlarge) A. Depiction of Human Airway. B. Human Bronchial Epithelial Cell (HBEpC). C. Crystal Violet Staining. D. Hematoxylin & Eosin Staining of HBEpC differentiated into pseudostriated epithelium after 28 days.
Details
The Airway Model (Domestic US) consists of HBEpC differentiated into a pseudostriated epithelium, whereas the Total Kit (international customers) contains Cryopreserved HBEpC, media, twelve PCF inserts, reagents, subculture kit, and detailed instructions to form 3D Airway Model.
Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| 3-D Airway Model : Cells, Media, Reagents & Inserts (See Details tab for specifics) | Size: 1 Kit | CAT.#: 502K-3D | Price: $769.00 | |
| 3-D Airway Model (Not available for international orders): HBEpC differentiated into pseudostriated epithelium on PCF sitting inserts. Available only in the US. Approximate turnaround time 4-6 weeks. | Size: 12 Sitting Inserts | CAT.#: 502-3D-12 | Price: $769.00 | |
| 3-D Airway Model (Not available for international orders): HBEpC differentiated into pseudostriated epithelium on PCF sitting inserts. Available only in the US. Approximate turnaround time 4-6 weeks. | Size: 24 Sitting Inserts | CAT.#: 502-3D-24 | Price: $1,355.00 |
Related Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| Cryopreserved Human Bronchial Epithelial Cell Total Kit, adult: 5x10^5 Cells (Adult), Medium & Subculture Reagents (See Details tab for specifics) | Size: 1 Kit | CAT.#: 502K-05a | Price: $938.00 | |
| Cryopreserved Bronchial Epithelial Cells (HBEpC), adult: Frozen HBEpC (5x10^5) | Size: 1 Cryovial | CAT.#: 502-05a | Price: $740.00 | |
| Bronchial Epithelial Cell RNA (HBEpC RNA), Adult: Total RNA prepared from Human Bronchial Epithelial Cells, adult | Size: 10 ug | CAT.#: 502-R10a | Price: $398.00 | |
| Bronchial Epithelial Cell RNA (HBEpC RNA), Adult: Total RNA prepared from Human Bronchial Epithelial Cells, adult | Size: 25 ug | CAT.#: 502-R25a | Price: $796.00 | |
| HBrEpC/HTrEpC Basal Medium: Without growth supplement (GS). Add GS before use. | Size: 500 ml | CAT.#: 510-500 | Price: $81.00 | |
| HBEpC/HTEpC Differentiation Medium: Promotes cells to change from one type to another, more specialized | Size: 250 ml | CAT.#: 511D-250 | Price: $148.00 | |
| HBEpC/HTEpC Growth Medium: All-in-one ready-to-use. Cat# 511-500 fully supports cell growth on its own. Retinoic acid (RA) is a optional component; one vial of RA goes into 500ml media. Some researchers may elect to include RA if studies include cell differentiation or pseudo-stratification. | Size: 500 ml | CAT.#: 511-500 | Price: $145.00 | |
| HBEpC/HTEpC Growth Medium wo BPE: Growth medium without BPE | Size: 500 ml | CAT.#: 511B-500 | Price: $144.00 | |
| HBEpC/HTEpC Growth Medium wo BPE, Hydrocortisone, Insulin: Growth medium without BPE, hydrocortisone and insulin | Size: 500 ml | CAT.#: 511BHI-500 | Price: $144.00 | |
| HBEpC/HTEpC Growth Medium wo T3: Growth medium without Tri-iodothyronine (T3) | Size: 500 ml | CAT.#: 511T3-500 | Price: $144.00 | |
| HBEpC/HTEpC Growth Medium wo Antibiotics: Growth medium without antibiotics | Size: 500 ml | CAT.#: 511A-500 | Price: $144.00 | |
| HBEpC/HTEpC Growth Medium Kit: Basal medium & growth supplement sold together packaged separately | Size: 1 Kit | CAT.#: 511K-500 | Price: $154.00 | |
| HBEpC/HTEpC Growth Supplement: Added to Basal Medium to create Growth Medium | Size: 5 ml | CAT.#: 511-GS | Price: $81.00 |
Extended Family Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| HBSS: 1X HBSS for washing of cells before Trypsin/EDTA treatment | Size: 100 ml | CAT.#: 062-100 | Price: $23.00 | |
| Trypsin/EDTA Solution: For subculturing of adherent cells. | Size: 100 ml | CAT.#: 070-100 | Price: $23.00 | |
| Trypsin Neutralization Solution: Stops the trypsinization reaction. | Size: 100 ml | CAT.#: 080-100 | Price: $23.00 | |
| Cyto-X Cell Counting Reagent Sample: 100 tests | Size: Sample | CAT.#: 028-S | Price: $41.00 | |
| Cyto-X Cell Counting Reagent: 500 tests | Size: 1 Bottle | CAT.#: 028-01 | Price: $160.00 |
Citations
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2009
Song, H., H. Wan, Y. Araya and D. Perez. 2009. Partial direct contact transmission in ferrets of a mallard H7N3 influenza virus with typical avian-like receptor specificity. 2009. Virology Journal, 6:126.
2007
Wan, H. and D. Perez. 2007. Amino Acid 226 in the Hemagglutinin of H9N2 Influenza Viruses Determines Cell Tropism and Replication in Human Airway Epithelial Cells. J Virol, 81:5181-5191.