Product Sheet CP10023
Description
BACKGROUND BDH1 (3-hydroxybutyrate dehydrogenase, type 1) is a member of the short-chain dehydrogenase/reductase family. This protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. It catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism.1
REFERENCES
1. Marks, A.R. et al: J. Biol. Chem. 267:15459-63, 1992
Products are for research use only. They are not intended for human, animal, or diagnostic applications.
(Click to Enlarge)
Top: Western Blot detection of BDH1 proteins in HepG2 and NIH3T3 cell lysates using BDH1 Antibody. Bottom: This antibody stains paraffin-embedded colon cancer tissue in immunohistochemical analysis.
Details
Cat.No.: | CP10023 |
Antigen: | Purified recombinant human BDH1-Fc fusion protein expressed in 293 cells. |
Isotype: | Mouse IgG1 |
Species & predicted species cross- reactivity ( ): | Human, Mouse |
Applications & Suggested starting dilutions:* | WB 1:500 - 1:2000 IP 1:25 - 1:50 IHC 1:200 ICC n/d FACS n/d |
Predicted Molecular Weight of protein: | 45 kDa |
Specificity/Sensitivity: | Detects endogenous BDH1 proteins in normal cell lysates without cross-reactivity with other related proteins. |
Storage: | Store at -20°C, 4°C for frequent use. Avoid repeated freeze-thaw cycles. |
*Optimal working dilutions must be determined by end user.
Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| Mouse 3-Hydroxybutyrate Dehydrogenase, Type 1 Antibody: Mouse 3-Hydroxybutyrate Dehydrogenase, Type 1 Antibody | Size: 100 ul | CAT.#: CP10023 | Price: $333.00 |