BACKGROUND Brain Derived Neurotrophic Factor, or BDNF, is a nerve growth factor that supports neuron growth and survival. BDNF shares identical domains with two other neurotrophic factors known as, β-NGF and NT-3 (neurotrophin-3). BDNF binds with low affinity to a receptor known as LNGFR, which also binds NGF and NT-3, but mediates survival function by signaling through a high affinity receptor known as gp145/TrkB. Human, mouse, rat and pig BDNF are all cross-reactive.
Recombinant human BDNF is a non-glycosylated homodimer containing two 119 amino acid chains, having a total molecular mass of 27 kDa.
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RP-HPLC calibrated against a known standard.
Quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
|Human Brain Derived Neurotrophic Factor (BDNF): Human Brain Derived Neurotrophic Factor||Size: 10 ug||CAT.#: RP1001-10||Price: $194.00|
|Human Brain Derived Neurotrophic Factor (BDNF): Human Brain Derived Neurotrophic Factor||Size: 100 ug||CAT.#: RP1001-100||Price: $624.00|
|Human Brain Derived Neurotrophic Factor (BDNF): Human Brain Derived Neurotrophic Factor||Size: 1000 ug||CAT.#: RP1001-1000||Price: $5,327.00|