Product Sheet RP4007
Product Sheet RP4007AF

Description

BACKGROUND  Epstein-Barr virus induced gene 3 (EBI3) is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12).  EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection.  EBI3 forms heterodimers with p28 to form interleukin 27 (IL-27), and with p35 to form interleukin 35 (IL-35).  Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.
 
Recombinant Macaque Epstein-Barr Virus Induced Gene-3 is a non-glycosylated protein monomer, containing 210 amino acids and having a molecular mass of 23.4 kDa.
 
Products are for research use only. They are not intended for human, animal, or diagnostic applications.     

Details

Cat. No.:
RP4007
 
Alternate Names:
IL-35/EBI3, IL-27 EBI3 subunit, IL-35 EBI3 subunit
 
Source:
E. coli
 
Physical Appearance:
Sterile Filtered white lyophilized (freeze-dried) powder.
 
Formulation:
0.1% Trifluoroacetic Acid (TFA)
 
Stability:
Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
 
Reconstitution:
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile 20 mM HCI at 0.1 mg/mL, which can be further diluted into other aqueous solutions.
 
Protein Content and Purity determined by:
• UV spectroscopy at 280 nm.
• RP-HPLC calibrated against a known standard.
• Quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
 
Endotoxin Level:
Endotoxin level, as measured by LAL analysis, is <0.01ng/ug or <0.1EU/ug.
 
AA Sequence:
MRKGPPAALT LPRVQCRAPR YPIAVDCSWT LPPAPNSTSP VSFIATYRFG MAARGHSWPC LQQTPASTSC TIADVRLFSM APYVLNVTAV HPWGSSSSFV PFIAEHIIKP DPPEGVRLSP LAERQLQVQW EPPRSWPFPE IFSLKYWIRY KRQGAARFHQ VGPIEATSFI LRAVRPRARY CVQVAAQDLT DYGELSDWSL PATTPMSPGK

Products

Product Size CAT.# Price Quantity
Macaque Epstein-Barr Virus Induced Gene 3 (EBI3): Macaque Epstein-Barr Virus Induced Gene-3 Size: 20 ug CAT.#: RP4007-20 Price: $78.00
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Macaque Epstein-Barr Virus Induced Gene 3 (EBI3): Macaque Epstein-Barr Virus Induced Gene-3 Size: 500 ug CAT.#: RP4007-500 Price: $294.00
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Macaque Epstein-Barr Virus Induced Gene 3 (EBI3): Macaque Epstein-Barr Virus Induced Gene-3 Size: 1000 ug CAT.#: RP4007-1000 Price: $1,645.00
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Resources/Documents