Product Sheet RP4003
Product Sheet RP4003AF

Description

BACKGROUND  Interleukin 8 (IL-8 or CXCL8) is a member of the CXC cytokine family and is produced by macrophages, epithelial, smooth muscle, and endothelial cells.  IL-8 binds the  G protein-coupled serpentine receptors CXCR1 and CXCR2.  IL-8 recruits innate immune cells, induces phagocytosis, and stimulate angiogenesis.
 
Recombinant Porcine Interleukin-8 is a non-glycosylated protein monomer, containing 78 amino acids and having a molecular mass of 9.1 kDa.
 
Products are for research use only. They are not intended for human, animal, or diagnostic applications.

Details

Cat. No.:
RP4003 / RP4003AF
 
Alternate Names:
CXCL8, neutrophil chemotactic factor
 
Source:
E. coli
 
Physical Appearance:
Sterile Filtered white lyophilized (freeze-dried) powder.
 
Formulation:
5 mM sodium phosphate, 20 mM sodium chloride, pH 7.5
 
Stability:
Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
 
Reconstitution:
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/mL, which can be further diluted into other aqueous solutions.
 
Protein Content and Purity determined by:
• UV spectroscopy at 280 nm.
• RP-HPLC calibrated against a known standard.
• Quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
 
Endotoxin Level:
Endotoxin level, as measured by LAL analysis, is <0.01ng/ug or <0.1EU/ug.
 
AA Sequence:
ARVSAELRCQ CINTHSTPFH PKFIKELRVI ESGPHCENSE IIVKLVNGKE VCLDPKEKWV QKVVQIFLKR TEKQQQQQ
 
Animal Component-Free
This product is produced with no animal derived raw products.  All processing and handling employs animal free equipment and animal free protocols.

Products

Product Size CAT.# Price Quantity
Porcine Interleukin 8 (CXCL8): Porcine Interleukin-8 Size: 20 ug CAT.#: RP4003-20 Price: $26.00
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Porcine Interleukin 8 (CXCL8): Porcine Interleukin-8 Size: 100 ug CAT.#: RP4003-100 Price: $470.00
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Porcine Interleukin 8 (CXCL8): Porcine Interleukin-8 Size: 1000 ug CAT.#: RP4003-1000 Price: $3,173.00
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Porcine IL-8, Animal-Free: Porcine IL-8, Animal-Free Size: 20 ug CAT.#: RP4003AF-20 Price: $215.00
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Porcine IL-8, Animal-Free: Porcine IL-8, Animal-Free Size: 100 ug CAT.#: RP4003AF-100 Price: $517.00
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Porcine IL-8, Animal-Free: Porcine IL-8, Animal-Free Size: 1000 ug CAT.#: RP4003AF-1000 Price: $3,490.00
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