Product Sheet RP1046
Description
BACKGROUND Neuregulin 1-beta (NRG-1β) is one of many alternatively-spliced isoforms of the NRG1 gene and contains a soluble EGF-like domain. The EGF-like domain of NRG-1β signals through the ErbB2, ErbB3, and ErbB4 receptor tyrosine kinases. NRG-1β is an important growth factor involved in neuroinflammation, nerve regeneration, and cardiovascular processes.
Recombinant human Neuregulin 1-beta is a non-glycosylated protein monomer, containing 66 amino acids and having a molecular mass of 7.6 kDa.
Products are for research use only. They are not intended for human, animal, or diagnostic applications.
Details
Cat. No.:
RP1046 / RP1046AF
Alternate Names:
NGR beta 1, heregulin, HRG1 beta
Source:
E. coli
Physical Appearance:
Sterile Filtered white lyophilized (freeze-dried) powder.
Formulation:
0.1% Trifluoroacetic Acid (TFA)
Stability:
Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
Reconstitution:
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Protein Content and Purity determined by:
• UV spectroscopy at 280 nm.
• RP-HPLC calibrated against a known standard.
• Quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
Endotoxin Level:
Endotoxin level, as measured by LAL analysis, is <0.01ng/ug or <0.1EU/ug.
AA Sequence:
MSHLVKCAEK EKTFCVNGGE CFMVKDLSNP SRYLCKCPNE FTGDRCQNY MASFYKHLGI EFMEAE
Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| Human Neuregulin-1 Beta (NRG-1 beta) : Human Neuregulin-1-beta | Size: 10 ug | CAT.#: RP1046-10 | Price: $78.00 | |
| Human Neuregulin-1 Beta (NRG-1 beta) : Human Neuregulin-1-beta | Size: 100 ug | CAT.#: RP1046-100 | Price: $317.00 | |
| Human Neuregulin-1 Beta (NRG-1 beta) : Human Neuregulin-1-beta | Size: 1000 ug | CAT.#: RP1046-1000 | Price: $1,410.00 |