PECAM-1/CD31 ELISA Kit, Human

Product Sheet CL0883

Description

BACKGROUND CD31, a member of the immunoglobulin superfamily, is a 130 kDa transmembrane glycoprotein also designated as PECAM-1 (platelet endothelial cell adhesion molecule1). CD-31 is normally found on endothelial cells (EC), platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, neutrophils.1 It plays a major role in the adhesion cascade between EC and the inflammatory cells during inflammation in facilitating leucocyte migration and between EC during angiogenesis.2,3 It has recently been recognized for its angiogenic role. It is one of the best markers for benign and malignant vascular tumors, but also stains plasma cells, monocytes, and megakaryocytes.4
 
REFERENCES  
1. Newman, P. J.. et al: Science 247: 1219, 1990.
2. Kalinowska, A. & Losy, J. : Eur. J. Neurol. 13:1284, 2007.
3. Stockinger, H. et al. (1991). J. Immunol. 145:3889, 1991.
4. Tang, D. G. et al: J. Biol. Chem. 268:22883, 1993.
 
Products are for research use only. They are not intended for human, animal, or diagnostic applications.
(Click to Enlarge) Platelet Endothelial Cell Adhesion Molecule/Cluster of Differentiation 31 (PECAM-1/CD31) Standard Curve: Using the Human PECAM-1 ELISA Kit, O.D. data was graphed against PECAM-1 protein concentration. The TMB reaction was incubated at 37°C for 25 min.

Details

Cat.No.:
CL0883
Target Protein Species:
Human
Range:
156pg/ml-10,000pg/ml
Specificity:
No detectable cross-reactivity
with any other cytokine.
Storage:
Store at 4°C. Use within 6 months.
 
ELISA Kits are based on standard sandwich enzyme-linked immunosorbent assay technology. Freshly prepared standards, samples, and solutions are recommended for best results.

Products

Product Size CAT.# Price Quantity
Human PECAM-1/CD31 ELISA Kit: Human Platelet Endothelial Cell Adhesion Molecule-1/Cluster of Differentiation 31 ELISA Kit Size: 96 Wells CAT.#: CL0883 Price: $587.00
-+

Resources/Documents