Product Sheet CL0884
Description
BACKGROUND CD31, a member of the immunoglobulin superfamily, is a 130 kDa transmembrane glycoprotein also designated as PECAM-1 (platelet endothelial cell adhesion molecule1). CD-31 is normally found on endothelial cells (EC), platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, neutrophils.1 It plays a major role in the adhesion cascade between EC and the inflammatory cells during inflammation in facilitating leucocyte migration and between EC during angiogenesis.2,3 It has recently been recognized for its angiogenic role. It is one of the best markers for benign and malignant vascular tumors, but also stains plasma cells, monocytes, and megakaryocytes.4
REFERENCES
1. Newman, P. J.. et al: Science 247: 1219, 1990.
2. Kalinowska, A. & Losy, J. : Eur. J. Neurol. 13:1284, 2007.
3. Stockinger, H. et al. (1991). J. Immunol. 145:3889, 1991.
4. Tang, D. G. et al: J. Biol. Chem. 268:22883, 1993.
2. Kalinowska, A. & Losy, J. : Eur. J. Neurol. 13:1284, 2007.
3. Stockinger, H. et al. (1991). J. Immunol. 145:3889, 1991.
4. Tang, D. G. et al: J. Biol. Chem. 268:22883, 1993.
Products are for research use only. They are not intended for human, animal, or diagnostic applications.
(Click to Enlarge) Platelet Endothelial Cell Adhesion Molecule-1/Cluster of Differentiation 31 (PECAM-1/CD31) Standard Curve: Using the Mouse PECAM-1 ELISA Kit, O.D. data was graphed against PECAM-1 protein concentration. The TMB reaction was incubated at 37°C for 25 min.
Products
| Product | Size | CAT.# | Price | Quantity |
|---|---|---|---|---|
| Mouse PECAM-1/CD31 ELISA Kit: Mouse Platelet Endothelial Cell Adhesion Molecule-1/Cluster of Differentiation 31 | Size: 96 Wells | CAT.#: CL0884 | Price: $533.00 |