Rat Kupffer Cell Media
Rat Kupffer Cell Media
Rat Kupffer Cell Culture Medium: All-in-one ready-to-use
Type: Culture Medium
Size: 100 ml
Price: $108.00
Description
Rat Kupffer Cell Media is a culture formulation designed to support the in vitro survival, attachment, and phenotypic maintenance of primary rat Kupffer cells. By providing nutrients and growth-supporting components, this medium helps maintain primary macrophage viability and function during culture.
Kupffer cells are resident macrophages of the liver and part of the mononuclear phagocytic system. They are located along the sinusoidal lining of hepatic tissue, in close association with liver endothelial cells and adjacent hepatocytes. Because the liver receives blood from the gastrointestinal tract via the portal circulation, Kupffer cells serve as an important immune surveillance population.
Functionally, these cells participate in phagocytosis of blood-borne pathogens, endotoxins, circulating antigens, and apoptotic cellular debris. They also contribute to immune and inflammatory signaling by producing cytokines and other mediators, and they are involved in drug-induced liver injury, chemical toxicity, and stellate cell activation during hepatic fibrosis.
Primary Kupffer cells can lose morphology and phagocytic activity in suboptimal culture conditions. Rat Kupffer Cell Media provides conditions intended to support stable, functional primary cultures in vitro.
This formulation is useful for immunology, hepatology, and toxicology research, including phagocytic assays, functional bioassays, immunocytochemistry (ICC), inflammatory signaling studies, xenobiotic toxicity, hepatic fibrosis, host-pathogen interactions, and liver-gut axis research.
Medium carefully optimized for the characteristics and requirements unique to Rat Kupffer Cell Media Cells. Attention to detail ensures ideal cell health, viability, performance, physiology, morphology, consistency and data.
Use with:
Details
CAI media are tested for sterility in order to confirm no bacteria, yeast or fungi contaminate the solutions. The products undergo further quality control for correct pH, osmolality and lack of endotoxins. A panel of different bioassays affirm the media sustain a proper environment for expected cell-type-specific culture, growth, plating, karyotype, physiology, morphology, viability, population doublings, surface markers, cryopreservation, differentiation and/or induction.
Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.